New opportunities to help us **deliver innovation** within our bioprocessing and fill/finish facilities.Oxford Biomedica is a pioneer of gene and cell therapy and our work is helping to deliver life changing treatments.Our facilities contain state-of-the-art bioprocessing technologies such as bioreactors, chromatography systems and purification/filtration systems. Similarly, our new fill/finish suites will contain bespoke-designed isolation technologies, automated filling systems, and sanitisation technologies to meet the demanding process requirements of our viral vector productsWe are therefore seeking qualified Scientists/Engineers to provide the technical expertise to Oxford Biomedica including technology transfer, new product introduction, manufacturing support, process troubleshooting, deviation investigations, change control, and continuous improvement. **Key Duties & Responsibilities** :* Actively participate in defining technical strategy for MSAT projects* Generate and review documentation supporting technology transfer and New Product Introduction (NPI). Define success criteria for technical transfer and provide expert evaluation of the technical outcomes.* Identify and lead continuous improvement opportunities relating to the manufacturing process.* Lead root cause investigations using a systematic approach to resolve complex problems and implementing solutions.* Writing of complex technical reports to a high standard* Gather, evaluate and analyse process data for manufacturing process robustness.* Develop relationships with new suppliers and service providers* May Suggest changes to MSAT in lines with Regulations and guidance documents and execute the updates linked to this change **Person Specification:** * Post-graduate degree in Biology/Biochemistry, Chemical/Biochemical Engineering or a related field.* Process development or GMP production experience required.* Specialist experience in technology transfer and/or new product introduction within sterile environment essential.* Expertise in the use / application of variety of problem solving tools and quality risk assessment methodologies would be ideal.* Understanding of theoretical and practical challenges of scale-up would be beneficial. **We look forward to receiving your application** **No agencies please**

Research Scientists in cell & molecular biologyDo you have the skills to help us push the boundaries in drug discovery by developing and implementing in vitro metabolic cell models and assays? Do you also believe that the chances of real scientific progress are at their best when we collaborate closely and cross-functionally? Then you may be one of the two Research Scientists we would like to welcome to our team. About Novo Nordisk Research Centre Oxford (NNRCO)Novo Nordisk is a leading global healthcare company, founded in 1923 and headquartered in Denmark. We employ more than 42,000 people in 80 countries and market our products in around 170 countries. Novo Nordisk Research Centre Oxford (NNRCO) is Novo Nordisk’s Translational Research Unit focused on biology and target discovery across the broad spectrum of cardiometabolic disease in Oxford, United Kingdom. Our location in the heart of the University of Oxford medical campus enables two-way collaborations with some of the best medical scientists in the world. We use genetics, functional genomics, human-centric disease models and computational biology to develop an unparalleled understanding of cardiometabolic disease and deliver therapies that transform the lives of patients.You can read more about Novo Nordisk Research Centre Oxford at: http://www.novonordisk.co.uk/about-novo-nordisk-in-uk/oxford-research-centre.htmlAbout the Department The Department of Discovery Technologies and Genomics has as its mission to establish and apply state-of-the-art genomics and screening technologies to discover and validate novel therapeutic targets for cardiometabolic diseases using human-centric in vitro approaches. Ultimately, our aim is to identify targets and key biology to discover new disruptive therapeutics.The department is led by Carina Ämmälä, and consists of specialists, staff scientists and post-doctoral scientists. We are a dedicated, collaborative team, working within a variety of advanced technologies, including high throughput screening, high content imaging, single-cell sequencing, CRISPR editing, functional genomics, proteomics, peptidomics, and statistical modelling. Together, we share a passion for translational research and a desire to discover new scientific paths to improve the lives of patients. The positionWe are looking for two Research Scientists to support our target discovery research. The primary goal in both positions will be to establish in vitro assays in primary human cell types relevant cardiometabolic disease, assays that will be used for identification and validation of novel innovative drug targets for treating cardiometabolic disease. You will be expected to use your cell and molecular biology skills to develop novel disease-relevant phenotypic cellular assays used in screening to identify novel targets, and for mechanism of actions studies to increase the biological understanding of promising targets.Moreover, there is a significant element of close collaboration within the NNRCO and with external partners. In the NNRCO you will work closely with automation and imaging experts to miniaturize, automate and optimize assays for high-throughput screening. You will also work with geneticists and computational scientists to develop data compelling packages and building evidence for clinical benefit to support target selection. Outside the NNRCO, you will engage with external partners through collaborations with universities and/or biotech companies. Finally, it is expected that the position holder show leadership within their field of expertise and mentor post docs and junior scientists. All of the above applies for both open positions, and we are very open to adjusting some aspects of the roles to fit your unique experience. Likewise, in this position you will also have the opportunity to propose and pursue your own scientific ideas aligned with the NNRCO ambition.QualificationsThe ideal candidate holds a PhD in molecular/cellular biology or related life science with significant experience working with human primary cells and cell-based assay development along with knowledge of the cellular/molecular mechanisms within an area related to cardiometabolic disease. Some relevant cell types and tissues are adipocytes, hepatocytes, Stella the cells, islet of Langerhans, kidney, muscle, and vascular cells. In addition, experience with vitro co-cultures and organoid models would be considered a plus.Hands on experience of additional technologies such as confocal imaging, flow cytometry, mass spectrometry or state of the art sequencing methodologies is desirable, and knowledge of the drug discovery process and in vitro screening systems (i.e. high-throughput screening) is an advantage.Both positions are lab based, so it is essential that candidates have a strong motivation for working hands-on in the lab, progressing science through well designed and robust in vitro experimental work. We always have several projects running, so we are looking for candidates who thrive working on multiple projects simultaneously and who can keep their cool even when there is pressure to deliver. Importantly, the right candidates will have a collaborative behaviour, and an entrepreneurial mindset. Salary indication: GBP 47.000 – 52.000 yearly ContactFor further information, please contact Director Carina Ämmälä on +44 782 460 6940Deadline28th July 2020

We are seeking to appoint a Research Associate in Behavioural Genetics / Genetic Epidemiology. Funding for the post is available for five years, until August 2025.This is a post-doctoral position, associated with a European Research Council (ERC) Starting Grant. It will involve quantitative analysis to explore the importance of gene-environment interactions within the developmental origins of health and disease. The project is based in the School of Economics, but it involves collaborations across multiple disciplines.Candidates must have a PhD in a quantitative subject, ideally in behavioural genetics, genetic epidemiology, statistical genetics, genoeconomics, or a related discipline. They must have a keen interest in working across disciplines. Experience analysing genome-wide data sources is required, as well as strong quantitative skills, and experience of using statistical software such as R or Stata.The closing date for applications is midnight on Thursday 23 July 2020. The proposed start date is 1 September 2020 or as soon as possible thereafter.For further information please contact Prof. Stephanie von Hinke; e-mail: S.vonHinke@bristol.ac.uk

There are two posts available, both full time working 35 hours per week. One is permanent, and one is fixed term until November 2022. The University of Westminster has been engaged in air transport research, consultancy and teaching for over 40 years. The air traffic management team is located within the School of Architecture and Cities, based at our Marylebone campus, in central London. Air traffic management has been a core area of research for over 20 years, with a very strong international reputation and with particular emphases on economics, operations, data analysis, modelling and performance. Following several successful H2020 project bids, we are now looking to expand this research area through the appointment of two Research Fellows.The postholders will work on these new projects with the air traffic management team, led by Professor Andrew Cook. The position requires individual and collaborative research, contributions to research bids, co-authored publication work and activities to promote impact and extend the team’s research portfolio, with a high standard of written and spoken English. The postholders will need to demonstrate skills and experience in data analysis, optimisation methods, and a range of machine learning algorithms and applications (such as predictive analytics and data mining/classification). Previous experience of analytical modelling and good numerical modelling skills (e.g. network simulation) must be demonstrated. (Knowledge of ensemble learning and of stochastic modelling would be an advantage.)The position requires the ability to work efficiently with high volumes of data, with experience of data cleaning, data fusion, and data storage/management. (Knowledge of NoSQL databases and secure data frames would be an advantage.)Candidates from disciplines outside the field of transport will be considered. Work in our team often draws on complex network metrics and measures of causality. Experience of European air traffic management principles and flight trajectory optimisation would be an advantage. The former must otherwise be acquired, with team support, in post.Shortlisted candidates will be contacted by e-mail by 30 July 2020 regarding interviews. Due to the prevailing Covid-19 situation, interviews will be conducted remotely, on 12 August 2020. Shortlisted candidates will be required to make a short, technical presentation as part of their interview, on a topic to be notified on shortlisting. The interview technical arrangements will be agreed in advance with the candidate (probably Skype). The successful candidate would start ASAP thereafter.It is likely that the initial period in post would be undertaken remotely, until such time as government guidance advises on the safety of the lifting of current restrictions. The ATM team uses remote tools extensively for its research collaborations in any case, such that issues are not foreseen with the postholder initially working remotely. No special tools are required.The successful applicant would be advised regarding initial contracting and payroll arrangements.For further information and to apply for this post, please click apply and you will be redirected to our website.Closing date: midnight on 23 July 2020Interviews are likely to be held on: 12 August 2020 Administrative contact (for queries only): Recruitment@westminster.ac.uk Please note: We are unable to accept applications by email. All applications must be made online. CVs in isolation or incomplete application forms will not be accepted. Embracing diversity and promoting equality.

This post is full time and permanent, working 35 hours per week.The University of Westminster has been engaged in air transport research, consultancy and teaching for over 40 years. The air traffic management team is located within the School of Architecture and Cities, based at our Marylebone campus, in central London.Air traffic management has been a core area of research for over 20 years, with a very strong international reputation and with particular emphases on economics, operations, data analysis, modelling and performance. Following several successful H2020 project bids, we are now looking to expand this research area through the appointment of a Senior Research Fellow.The postholder will work on these new projects with the air traffic management team, led by Professor Andrew Cook. The position requires individual and collaborative research, contributions to research bids, co-authored publication work and activities to promote impact and extend the team’s research portfolio, with a high standard of written and spoken English.The position requires excellent knowledge of the evolving European transport system, including the aviation perspective, particularly from a behavioural and economic perspective. Good awareness of previous and on-going research and development is required, with detailed knowledge of European high-level agendas, policies and goals, such as ACARE’s Strategic Research and Innovation Agenda.The postholder will need to demonstrate experience across a range of transport modelling methods, such as: analytical modelling; network simulation; multi-modal and variable demand models; value of time and stated preference methods; strategic supply and demand; stochastic models.Knowledge of (emerging) intelligent mobility solutions is required, such as: MaaS; travel management tools; autonomous vehicles; digital, connected consumers; future passenger profiling and segmentation. Expertise regarding transport data availability (e.g. passenger flows, surveys) and the ability to clean and critically analyse large datasets must be demonstrated.Shortlisted candidates will be contacted by e-mail by 30 July 2020 regarding interviews. Due to the prevailing Covid-19 situation, interviews will be conducted remotely, on 13 August 2020. Shortlisted candidates will be required to make a short, technical presentation as part of their interview, on a topic to be notified on shortlisting. The interview technical arrangements will be agreed in advance with the candidate (probably Skype). The successful candidates will start ASAP thereafter. It is likely that the initial period in post would be undertaken remotely, until such time as government guidance advises on the safety of the lifting of current restrictions. The ATM team uses remote tools extensively for its research collaborations in any case, such that issues are not foreseen with the postholder initially working remotely. No special tools are required. For further information and to apply for this post, please click apply and you will be redirected to our website.Closing date: midnight on 23 July 2020Interviews are likely to be held on: 13 August 2020 Administrative contact (for queries only): Recruitment@westminster.ac.uk Please note: We are unable to accept applications by email. All applications must be made online. CVs in isolation or incomplete application forms will not be accepted. Embracing diversity and promoting equality.

We welcome and encourage applications from everyone, including groups currently underrepresented in our workforce and pride ourselves as being an employer of choice. To find out more about how we champion diversity and inclusion in the workplace, visit: https://www.gov.uk/government/organisations/ministry-of-justice/about/equality-and-diversityOverview Do you have the passion, values and ability to make a real difference to solving the UK`s biggest issues? Now is an exciting time to join the Government Statistical Group (GSG) as a professional statistician. The Government Statistical Service (GSS) collects, analyses and publishes official statistics to help government, business, and the public understand the current state of the UK economy and society. The Ministry of Justice is offering you the opportunity to work on high profile analysis and research across the criminal justice system. You will work with energy and pace on analysis and research which is likely to involve using large administrative data sources. Whilst we hope you will decide to have a long career in the Ministry of Justice, being a member of the GSG will allow you to consider other posts and locations across government departments as your career progresses.The Data & Analytical Services Directorate (DASD) within the Ministry of Justice is looking to recruit: • Senior Statistical Officers (Band Bb/Senior Executive Officer Equivalents), • Higher Statistical Officers (Band Cb/Higher Executive Officer Equivalents) and • Statistical Officers (Band Db/Executive Officer Equivalents) All roles are available for postings in London and Leeds. Typically, we would expect new graduates to be applying for entry at Band Db (Executive Officer equivalent). Appointments made will be on a permanent basis. We will be holding a merit list for 12 months to cover future Statistical roles and there are 6 campaigns running in total.If you wish to apply for one of the other campaigns mentioned above then please see the relevant campaign as listed below:1. Band Db London – 35149 External Recruitment for Statistical Officers in London2. Band Db Leeds – 35153 External Recruitment for Statistical Officers in LeedsThe Band Db grade will require you to apply your statistical skills to innovate and solve problems in data management and analysis. You will be using a range of software packages and analytical techniques. The ability to explain and communicate your findings to a varied audience will also be essential. This is typically the graduate entry grade.1. Band Cb London – 35148 External Recruitment for Higher Statistical Officers in London2. Band Cb Leeds – 35152 External Recruitment for Higher Statistical Officers in LeedsThe Band Cb grade will require you to apply your statistical skills to innovate and solve problems in data management and analysis. You will be using a range of software packages and analytical techniques. The ability to explain and communicate your findings to a varied audience will also be essential. This is typically the grade for those with a couple of years of experience of working in a statistical environment. A fuller range of competencies and behaviours will need to be demonstrated at interview (than for Band Db). 1. Band Bb London – 35147 External Recruitment for Senior Statistical Officers in London2. Band Bb Leeds - 35150 External Recruitment for Senior Statistical Officers in LeedsThe Band Bb grade will require you to take responsibility for multiple aspects of statistical production. Often managing teams of analysts and non-analysts to deliver innovative results for your stake holders. Developing expertise in technical skills through further training. This is typically the grade for those with a number of years of experience of working in a statistical environment. A fuller range of competencies and behaviours will need to be demonstrated at interview (than for Band Cb).

We are currently seeking applications for a Renewables Science Advice Leader within the Marine Scotland based in Aberdeen or Edinburgh. This is a permanent and pensionable appointment and new entrants will normally start on the minimum of the pay range. Candidates with a disability who meet the essential criteria below will be invited to the assessments.The Renewables Science Advice Leader will ensure the provision of high quality scientific advice on renewable energy and major construction project licensing and policy in Scotland's seas. This will involve rigorous quality control and quality assurance of the advice produced by the specialist advisors within MSS on a range of environmental receptors including marine mammals, seabirds, fish, fisheries, benthic ecology and physical processes. The post will ensure delivery of authoritative scientific advice to within government. They will develop excellent collaborative working with industry, academia and representatives from Scottish, UK and overseas governments.Qualifications RequiredFor jobs in Band B & C you must hold a minimum of 3 Highers or equivalent.Other qualifications equivalent to these may also be acceptable, if you are in any doubt please contact to discuss. Please note: If you fail to demonstrate how you meet the minimum qualifications as stated above, your application will be automatically sifted out.Essential Criteria1. A sound understanding of, and experience of applying, quantitative approaches usedIn environmental assessments and Habitat Regulation Appraisals of marine renewables or other licenced marine activities.2. A demonstrably good understanding of regulation and legislation relating to marinerenewables or other licenced marine activities.3. The ability to work independently with good organisational skills and effectively manage projects.4. Experience of ensuring the successful delivery of advice or technical documents to a range of stakeholders/ clients, ensuring that appropriate quality assurance processes are followed.Further InformationFor further details and to apply online, visit our website at http://bit.ly/sgvacancies. To apply, you must fully complete and submit an online application via our website before the closing date. To learn more about this opportunity, please contact Jared Wilson who can be reached at jared.wilson@gov.scot or 0131 244 9103.If you experience any difficulties accessing our website or completing the online application form, please contact HR Resourcing Team via at recruitment@gov.scot

We are currently seeking applications for a Renewables Science Projects Leader within the Marin Scotland based in Aberdeen or Edinburgh. This is a permanent and pensionable appointment and new entrants will normally start on the minimum of the pay range. Candidates with a disability who meet the essential criteria below will be invited to the assessments.The Renewables Science Projects Leader will ensure the development and delivery of renewables science projects within REEA, the identification and pursuit of relevant funding opportunities for MSS, and that the organisation as a whole has access to appropriate system and processed for effective costing, approval and delivery of external contracts and other income streams. This role will involve close liaison with colleagues across Marine Scotland and a collaborative approach with both internal and external stakeholders, and potential delivery partners. The post will maintain and enhance relationships with international partners to further enable collaborative working and accessing of external funding streams.Qualifications RequiredFor jobs in Band B & C you must hold a minimum of 3 Highers or equivalent.Other qualifications equivalent to these may also be acceptable, if you are in any doubt please contact to discuss. Please note: If you fail to demonstrate how you meet the minimum qualifications as stated above, your application will be automatically sifted out.Essential Criteria1. A good understanding of the marine environment and the potential impacts of anthropogenic activities upon key marine ecological receptors.2. Experience of leading the successful development of commercial, research or scientific project proposals, including development of collaborative partnerships and the gaining of appropriate funding.3. The ability to work independently with good organisational skills and effectively manage projects.4. Track record of successfully managing and delivering research, scientific or technical projects to time and to budget, including the use of appropriate project management tools.Further InformationFor further details and to apply online, visit our website at http://bit.ly/sgvacancies. To apply, you must fully complete and submit an online application via our website before the closing date. To learn more about this opportunity, please contact Jared Wilson who can be reached at jared.wilson@gov.scot or 0131 244 9103.If you experience any difficulties accessing our website or completing the online application form, please contact HR Resourcing via recruitment@gov.scot

**Be Inspiring ** and help us succeed together through passion, commitment and team work.We are looking for motivated people who want to make a difference, delivering advanced innovative treatments to patients with unmet needs and join us at our new facility. **Key responsibilities and accountabilities:** * Large scale manufacture of ATMPs within GMP cleanroom facilities including:* Upstream adherent and/or suspension mammalian cell culture, transfection and harvest of viral vector products.* Downstream processing including clarification, chromatography, ultra/diafiltration and fill/finish activities.* Ensuring batch success by working using good aseptic techniques.* Preparing, cleaning and maintaining the GMP facility including performing viable and non-viable environmental monitoring.* Preparation of growth media and stock solutions using portable mixing tanks.* Completing Batch Manufacturing Records in a timely fashion throughout the manufacturing process.* Taking part in continuous improvement initiatives & development of production processes.* Investigating quality incidents, deviations and improving procedures.* Working to high standards of health & safety. **Key skills and requirements:** * BSc Life Sciences or equivalent or experience of working within a biological or chemical GMP manufacturing environment.* Prior experience of working within an aseptic environment is advantageous but not essential.* Self-motivated with a strong focus on safety, quality, details and results.* Good problem solving, interpersonal communication and team skills.* Excellent writing skills and computer literacy.* Flexibility to work shifts (07:00 - 15:00 and 14:00 22:00) as dictated by the manufacturing schedule. **We look forward to receiving your application.** **No agencies please.**

A 3 year postdoctoral research position is available in Dr James Hodge’s lab in School of Physiology, Pharmacology and Neuroscience at University of Bristol. It will be in collaboration with Drs Katie Lunnon, Jon Witton (University of Exeter), Owen Peters and Gaynor Smith (Cardiff University). The Alzheimer’s Research UK funded grant is entitled “Functional screening of novel genes associated with Alzheimer’s disease (AD) to investigate new mechanisms, therapeutic targets and drugs”. Sequencing of people with AD has identified ~20 new genes associated with the risk of developing AD however it is unclear how these genes contribute to the disease. Furthermore co-supervisor Dr Katie Lunnon has identified another 20 epigenetic genes associated with AD. Many of these novel AD genes have never been studied before in any living organism. To address this bottleneck in AD research, we will use the fruit fly Drosophila which is an established genetic model to screen through the mutations in novel AD genes measuring the effects on neurodegeneration, lifespan, memory and sleep loss. We will determine the interaction between these novel neurodegenerative AD genes and human amyloid-Beta and tau and then characterise the function and mechanism of action of the novel AD genes. We will see if we can reverse AD-like pathology by correcting the novel AD mutants using genetics, this will show how they cause AD and their potential as drug targets. A degree and PhD in biomedical science is required and experience in Drosophila, molecular genetics, imaging, behaviour, pharmacology, electrophysiology and bioinformatics preferable, although training will be provided. Applicants will benefit from the state of art facilities, expertise and training available in Faculty of Life Sciences, University of Bristol. For informal enquiries please contact Dr James Hodge, email: james.hodge@bristol.ac.uk or tel: +44 (0) 117 331 1416. You can also see the following for more information: http://www.bristol.ac.uk/phys-pharm-neuro/people-new/hodge/ https://www.youtube.com/watch?v=MoS-9HgzCrohttp://www.bristol.ac.uk/phys-pharm-neuro/events/fly-meetings/https://twitter.com/doctor_fruitfly We welcome applications from all members of our community and are particularly encouraging those from diverse groups, such as members of the LGBT+ and BAME communities, to join us.