University of Oxford
we are looking for a capable and ambitous postdoctoral research scientist to work on an emerging collaborative project between the radcliffe department of medicine and the novonordisk research centre oxford. the appointee will take primary responsibility for the day to day conduct of a research project that builds on an existing programme of work and examines how disordered innate immune function (pro-inflammatory) characteristics of innate immune cells can be reprogrammed through ‘metabolic’ interventions. the appointee with be based in the radcliffe department of medicine in a laboratory (prof r choudhury), which is focused determining the factors determining innate immune function in atherosclerosis, diabetes and myocardial infarction, and will be an important link between that laboratory and the novonordisk research centre oxford. as postdoctoral researcher you will participate in general laboratory roles and responsibilities, shared with other lab members and work in the laboratory on the core research project. you will also be required to collaborate on internal and external allied projects. you will hold a relevant phd/dphil/md with relevant experience and have a high level of motivation for biomedical research. this is a full time appointment on a fixed term contract for 3 years and you will be based at the west wing, john radcliffe hospital, oxford and novonordisk research centre, oxford (collaboration base) applications for this vacancy are to be made online; you will be required to upload a cv and supporting statement which explains how you meet the selection criteria for the post. only applications received before 12.00 midday on 13 november 2020 can be considered. interviews are scheduled to place in late november. the university is an equal opportunity employer
University of Oxford
4 дней назад
postdoctoral research associate - microbiologyndm experimental medicine, john radcliife hospital, oxford grade 7: £32,817 - £40,322 p.a. we are seeking a post-doctoral research assistant - microbiology, with experience in molecular and culture-based microbiology to join an established multi-disciplinary team as part of modernising medical microbiology (mmm) consortium. as our post-doctoral research assistant, you will coordinate and undertake the microbiology component of a project seeking to use single-cell fluorescence microscopy to directly detect bacteria in clinical samples for species identification and antimicrobial resistance profiling. the project will expand on proof-of-principle work by first evaluating laboratory and clinical strains of common pathogenic species (escherichia coli and staphylococcus aureus), progressing to simulated and then clinical samples before finally undertaking a head-to-head evaluation of the optimised microscopy approach against routine diagnostic methods. although the post will be based at the john radcliffe hospital it is anticipated you will spend time with the physics and image processing teams to acquire additional skills related to high-resolution microscopy and image processing. you will hold a phd/phil in microbiology or a related subject with strong microbiology laboratory skills. you will be a good communicator, with the ability to learn skills quickly and a proven publication record. you will also have an interest in working collaboratively with researchers from different disciplines. the post is full time and fixed-term for up to 36 months starting from 1 february 2021. flexible working arrangements will be considered. applications for this vacancy are to be made online. you will be required to upload a supporting statement and cv as part of your online application. only applications received before 12.00 midday on 13 november 2020 will be considered. « return to the search results
5 дней назад
cardiff, cardiff county
we have an exciting opportunity for an enthusiastic, flexible and experienced individual to join our team of experts who produce radiopharmaceuticals to good manufacturing practices (gmp) standards in purpose designed facilities. we are seeking a highly motivated individual, with attention to detail, who demonstrates initiative and who will ensure that all work is carried out in compliance with local sops, gmp and mhra guidelines. as the successful candidate you will be given a unique opportunity to participate in the production of a range of established and new pet radiotracers for clinical use. you will participate in an active rota of production and dispensing and quality control of radiopharmaceuticals, operating a range of automated and manual radiochemical synthesis and quality control equipment. you will be involved in a wide range of tasks, assisting in all aspects of operating and maintain the facility to gmp standards, including equipment and laboratory maintenance, environmental monitoring, incoming materials management, and stock control. the post provides an opportunity to provide technical expertise and be involved in in new product introduction development of new techniques. the new team member will author and participate in completion of gmp documentation for all aspects of production and quality control. applicants should have a degree in a relevant science subject along with experience in at least one of the following:• aseptic dispensing procedures and environmental monitoring• excellent analytical instrumentation skills such as high-performance liquid chromatography (hplc), gas chromatography (gc), and tlc, including method development and validation• experience in operation of automated process equipment for gmp compliant pharmaceutical manufacturing• quality control procedures necessary for the safe production of a gmp compliant radiopharmaceutical production facility. proficiency in microsoft office (word, excel) is essential. previous experience with providing specialist technical support for production and quality control equipment, as well as working in a regulated environment (gmp, glp) is preferred.the wales research and diagnostic pet imaging facility is a state-of-the-art pet centre. equipment includes an iba18/9 cyclotron with a range of targets, gravatom hot cells hosting synthera, fastlab and trasis radiochemistry systems, automated dispensing systems and a fully equipped quality control laboratory with high performance liquid chromatography, thin layer chromatography, multi-channel analysis, endotoxin and ph meters. this post is full time (35 hours per week), open ended and is immediately available if you would like to know more about this position, then please contact dr peter llewelyn on 02920 742005please be aware that the typical working day will begin at 6am and that there will be a requirement to work saturdays on a rota basis. there may also be a need on occasions to work flexibly with a possible start time from 4.00am. salary: £27,511 - £31,866 per annum (grade 5)date advert posted: tuesday, 13 october 2020closing date: friday, 13 november 2020please be aware that cardiff university reserves the right to close this vacancy early should sufficient applications be received.cardiff university is committed to supporting and promoting equality and diversity and to creating an inclusive working environment. we believe this can be achieved through attracting, developing, and retaining a diverse range of staff from many different backgrounds. we therefore welcome applicants from all sections of the community regardless of sex, ethnicity, disability, sexual orientation, trans identity, relationship status, religion or belief, caring responsibilities, or age. in supporting our employees to achieve a balance between their work and their personal lives, we will also consider proposals for flexible working or job share arrangements. « return to the search results
Quantum Science Ltd
5 дней назад
role overviewquantum science ltd (qs) is seeking a senior surface chemist to join our r&d team based in daresbury, uk. the senior surface chemist will take a lead role in surface modification and functionalisation of nanomaterials. as a member of the team, you will have the opportunity to work on exciting projects to advance the company’s research and development. you will be given the flexibility to succeed and are provided avenues to reach your individual career goals while fulfilling the company’s mission.the work environment is fast-paced and requires comprehension and resolution of complex problems. a high level of self-discipline, initiative, and motivation is required as you will need to handle and prioritise multiple tasks simultaneously, with minimal supervision. diligence towards meeting project requirements on schedule is essential. company and business overviewquantum science is a leading material innovation company with strong portfolio of intellectual properties. we contribute to society through material innovations to transform image sensors for next generation smart phone, advanced driver-assistance systems and industrial automation, to change the way we detect diseases, and to introduce more efficient and cost-effective membrane technology for clean water. we have fostered strong relationships with leading research organisations and industrial partners to keep us at the forefront of innovation while achieving a stable foundation thanks to investors who share our long-term vision. several of our r&d team innovators are from top universities in the world. we work closely with research and business partners to develop innovative technologies and then license the developed technologies to create a win-win partnership with our customers.our company is based in daresbury national laboratory, warrington. main tasks and responsibility• provide technical lead in surface modification and functionalisation of nanomaterials to make them compatible with the host matrix and/or enhance their performance as required.• plan the research and experimental strategies for different type of materials includeo synthesis of novel organic, inorganic compounds and polymerso surface ligand exchange, surface passivation, surface-initiated polymerisation and bio-conjugationo modification and functionalisation of polymerso formulation development of nanomaterials in host matrixo fabrication of thin film using different coating techniques• carry out routine characterisation of materials using different techniques for organic, inorganic compounds and polymers, nanoparticles and thin films• analyse data and suggest solutions to improve target properties• provide guidance and technical support to other team members• prepare progress technical reports, invention disclosure/patents clearly and accurately in timely manner to provide competitive advantage and protect qs’s ip• actively contribute ideas to the team and the company. skills and experience• a phd in chemistry, material science or equivalent degree with proven research record in surface chemistry and interfaces science. preferred independent post-doc or research fellow or relevant industrial experience• must have deep understanding nanoparticles surface processes and extensive research in surface modification and functionalisation of nanoparticles, crosslinking chemistry and coating methodologies• experience in synthesis of small organic, inorganic compounds, polymerization reactions, polymer grafting and modification• preferred experience in bio-conjugation chemistry• excellent record of scientific research papers published in high impact factor journals and patents particularly in the field of surface chemistry of nanoparticles• require to be creative and innovative to generate and implement ideas• ability to plan, prioritise and address forthcoming issues• multitasking capabilities• strong organisation and influencing skills to effectively work with inter-disciplinary and cross-functional teams within qs or of external partners to achieve project goals• prior experience in grant or proposal writing, scientific journals review is a plus• excellent verbal and written communication skills including it literacy (microsoft word, excel, powerpoint). kpi’s:• achieving project milestones• reporting results to head of r&d in a timely manner• all invention disclosures/ patents filed in a timely manner• all samples are sent to other teams and customers in a timely manner• identify needed equipment and carry out procurement if necessary benefits package• competitive salary• performance-related bonus system• pension contribution• life insurance qualified candidates should send the cv to hr by 13 november 2020.
Quantum Science Ltd
5 дней назад
role overviewquantum science ltd (qs) is seeking a senior surface chemist to join our r&d team based in daresbury, uk. the senior surface chemist will take a lead role in surface modification and functionalisation of nanomaterials. as a member of the team, you will have the opportunity to work on exciting projects to advance the company’s research and development. you will be given the flexibility to succeed and are provided avenues to reach your individual career goals while fulfilling the company’s mission.the work environment is fast-paced and requires comprehension and resolution of complex problems. a high level of self-discipline, initiative, and motivation is required as you will need to handle and prioritise multiple tasks simultaneously, with minimal supervision. diligence towards meeting project requirements on schedule is essential.company and business overviewquantum science is a leading material innovation company with strong portfolio of intellectual properties. we contribute to society through material innovations to transform image sensors for next generation smart phone, advanced driver-assistance systems and industrial automation, to change the way we detect diseases, and to introduce more efficient and cost-effective membrane technology for clean water. we have fostered strong relationships with leading research organisations and industrial partners to keep us at the forefront of innovation while achieving a stable foundation thanks to investors who share our long-term vision. several of our r&d team innovators are from top universities in the world. we work closely with research and business partners to develop innovative technologies and then license the developed technologies to create a win-win partnership with our customers.our company is based in daresbury national laboratory, warrington.main tasks and responsibility• provide technical lead in surface modification and functionalisation of nanomaterials to make them compatible with the host matrix and/or enhance their performance as required.• plan the research and experimental strategies for different type of materials includeo synthesis of novel organic, inorganic compounds and polymerso surface ligand exchange, surface passivation, surface-initiated polymerisation and bio-conjugationo modification and functionalisation of polymerso formulation development of nanomaterials in host matrixo fabrication of thin film using different coating techniques• carry out routine characterisation of materials using different techniques for organic, inorganic compounds and polymers, nanoparticles and thin films• analyse data and suggest solutions to improve target properties• provide guidance and technical support to other team members• prepare progress technical reports, invention disclosure/patents clearly and accurately in timely manner to provide competitive advantage and protect qs’s ip• actively contribute ideas to the team and the company.skills and experience• a phd in chemistry, material science or equivalent degree with proven research record in surface chemistry and interfaces science. preferred independent post-doc or research fellow or relevant industrial experience• must have deep understanding nanoparticles surface processes and extensive research in surface modification and functionalisation of nanoparticles, crosslinking chemistry and coating methodologies• experience in synthesis of small organic, inorganic compounds, polymerization reactions, polymer grafting and modification• preferred experience in bio-conjugation chemistry• excellent record of scientific research papers published in high impact factor journals and patents particularly in the field of surface chemistry of nanoparticles• require to be creative and innovative to generate and implement ideas• ability to plan, prioritise and address forthcoming issues• multitasking capabilities• strong organisation and influencing skills to effectively work with inter-disciplinary and cross-functional teams within qs or of external partners to achieve project goals• prior experience in grant or proposal writing, scientific journals review is a plus• excellent verbal and written communication skills including it literacy (microsoft word, excel, powerpoint).kpi’s:• achieving project milestones• reporting results to head of r&d in a timely manner• all invention disclosures/ patents filed in a timely manner• all samples are sent to other teams and customers in a timely manner• identify needed equipment and carry out procurement if necessarybenefits package• competitive salary• performance-related bonus system• pension contribution• life insurancequalified candidates should send the cv to firstname.lastname@example.org by 13 november 2020. « return to the search results
University of Warwick
6 дней назад
university of warwick
full time (36.5 hours per week) fixed term contract for 24 months initially with the possibility of an extension up to 36 months. funding is available on fa6 for a research fellow for 24 months initially, with the possibility of an extension up to 36 months dependent on the work remaining and available funding; any such extension might have to be shortened up to a max 33 months dependent on the starting salary of the successful candidate. we are looking to develop a strong team of postdoctoral scientists to work on a project funded by the gordon and betty moore foundation within the research group of orkun soyer. in this project, we aim to understand the relations between spatial organization and metabolic interactions among microorganisms found in aquatic environments. using phototrophic granules and biologically generated mineral nodules from freshwater and marine environments as our model systems, we will combine approaches from microbial physiology, biophysics, and microfluidics to quantify and model spatial organization and metabolic interactions within these systems. we have already recruited one postdoctoral researcher with microbiology background and are now looking to hire a postdoctoral research assistant with complementary skills in biophysics, chemistry, physics, or systems biology. the successful candidate will work on studying metabolism-spatial organisation feedback in natural and synthetic communities composed of species found in the above-mentioned systems. this will entail tracking spatial organisation and metabolic interactions using tools such as fluorescent microscopy, microfluidics, microprobes, and metabolomics. the ideal candidate should have a background in microbial physiology, biophysics (soft matter), analytical chemistry, or related fields. s/he should be familiar with some of the complementary techniques expected to be used in this project, and as listed above. if you have not yet been awarded your phd but are near submission or have recently submitted your phd, any offers of employment will be made as research assistant on level 5 of the university grade structure (£30,046). upon successful award of your phd and evidence of this fact, you will be promoted to research fellow on the first point of level 6 of the university grade structure (£30,942 pa). job description job description undertake research in order to support the work of the department and develop and enhance its reputation, both internally and externally. assist the project leader and, where appropriate, project collaborators in the successful execution of the project. duties & responsibilities research help establish a sound research base within the department in order to assist the development of research objectives and proposals for own or joint research. conduct individual and collaborative research projects. to publish research outcomes in appropriate journals of international standing and to publish and disseminate the result of research to other reputable outlets. translate knowledge of advances in the subject area into research activity. may contribute to preparing proposals and applications to external bodies, e.g. for funding and contractual purposes, to support a developing research agenda. may present information on research progress and outcomes to bodies supervising research, e.g. steering groups. may contribute to the preparation of papers for steering groups and other bodies. communicate complex information (orally and in writing) and material of a specialist or highly technical nature. continually update own knowledge and understanding in field or specialism. teaching and learning support could be expected to contribute to the teaching and learning programmes in the department. assist in the supervision of student projects and the development of student research skills. may be involved in the assessment of student knowledge and supervision of projects. administration and other activities may be required to attend departmental meetings and to participate (where necessary) in other committees and working groups within the department, the faculty and the university. ensure compliance with health and safety in all aspects of work. work within budget constraints. the duties and responsibilities outlined are not intended to be an exhaustive list but provide guidance on the main aspects of the job. you will be required to be flexible in your duties.
King's College London
6 дней назад
job description this is a two-year position is for a technical research assistant with experience in the running of immunology assays, including cell culture, flow cytometry and biochemical assays. the role focuses on supporting a larger research team in the study of whether an unique potential for activating t cells is provided by proprietary antibody-based reagents that have been developed by the study sponsor (elstar therapeutics) and that engage germline-encoded domains of the v-beta chains of the alpha-beta t cell receptor. this is an extremely important project for several reasons. adrian hayday's laboratory has identified a set of butyrophilin-like (btnl) molecules that critically regulate gamma delta t cell selection and maturation by engaging engage germline-encoded domains of the v-gamma chains of the gamma-delta t cell receptor. moreover, the laboratory has proposed that the unique biological activities of btnls reflects their site-of-engagement on the tcr. if analogous signalling is induced by antibody-based reagents that engage analogous sites on v-beta, the “hayday hypothesis” would receive strong support, and would argue that t cell receptors should no longer be viewed entirely as clonotypic receptors activated by antigens engaging exclusively unique cdr3 motifs. this would provide a new biological paradigm for human t cell regulation. the proprietary reagents provided by elstar offer an unique opportunity to investigate this. there is intense interest in mechanisms by which t cells can be activated without inducing widespread cytokine release and other aspects of hyperactivation that are commonly associated with the use of the pan t cell activator, anti-cd3. clearly, v-beta-specific reagents potentially offer a means to activate a defined subset of t cells with immunotherapeutic potential. any identification of an unique signalling induced by engaging v-beta could form the basis of a screen for identifying endogenous, btnl-like molecules that naturally regulate alpha-beta t cells. this post will provide invaluable experience and an opportunity to work in an internationally respected laboratory as well as gaining experience of working with private sector biotech company. the post holder will be based in the laboratory of professor adrian hayday which has three main locations: the programme in infection and immunity, floor 2, borough wing; cibci, new hunt's house; and the francis crick institute. contract: fixed-term until 30 june 2022 hours: full-time- 35 hours per week key responsibilities processing of human blood/tissue samples and isolation of pbmcs/tissue resident t-cells for downstream experiements implementing methodologies and running assays used for the characterization of t cell activation using tcr v-beta specific antibodies functional in vitro t-cell assays/tissue culture operating flow cytometers and assisting with the maintenance of the instruments. running biochemical assays, such as western blot, to investigate signalling pathways downstream of antigen independant tcr activation. preparation of rna and dna from cell samples for use in various sequencing assays organisation and record keeping of reagent libraries undertake any other reasonable duties that may be relevant to the role the above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post. skills, knowledge, and experience essential criteria bsc/msc in a relevant discipline (e.g.immunology; life-sciences; biotechnology) over 3 years experience working in the field of immunology experience in running flow cytometry and/or biochemical assays is desirable experience in running tissue culture and fucntional t-cell experiments practical experience in running sops and working in a laboratory environment experience working with in vivo cancer models a keen interest in immunology and translational medicine is essential you will need to be self motivation and the have the ability to work independently with the support of the greater research team the ability to interperate scientific data and take thorough lab notes is a must. good communication skills and the ability to present data confidently and clearly is required. further information this post is subject to occupational health clearance. this advertisement does not meet the requirements for a certificate of sponsorship under home office regulations and therefore the university will not be able to offer sponsorship for this role.
University of Southampton
6 дней назад
there is an opportunity for a statistician to join a friendly team at the medical research council lifecourse epidemiology unit (leu) in southampton (director professor cyrus cooper). the leu aims to understand the environmental causes of diabetes, obesity, cardiovascular disease and osteoporosis, and to develop strategies to prevent them. its research is grouped into six themes: (1) musculoskeletal health in late life; (2) determinants of musculoskeletal health in mid-life; (3) early development and musculoskeletal health in adult life; (4) developmental determinants of cardiometabolic health and human capital: transitioning populations; (5) cardiometabolic health and human capital: integrative biology approaches to lifecourse health; and (6) developmental determinants of cardiometabolic health: behavioural systems. the post-holder would work mainly in programme 4, which is led by prof caroline fall and studies how maternal health and nutrition influences fetal development and later outcomes such as intelligence, body composition and adult cardio-metabolic disease (diabetes and cardiovascular disease) in the offspring. it is based in developing countries, especially in india and africa. the postholder’s main role will to analyse data from these projects. the post does not require overseas travel, but does involve frequent virtual interaction with researchers overseas. you will hold a phd or equivalent professional qualifications and experience in statistics or another relevant discipline (recent masters graduates welcome). experience with stata or spss, and some previous research experience, are essential. this is a full time or part-time position fixed term until june 30th 2021, potentially extendable dependent on performance and funding. for informal enquiries contact prof caroline fall (email@example.com) or dr kalyanaraman kumaran (firstname.lastname@example.org). application process: you should submit your completed online application form at https://jobs.soton.ac.uk. the application deadline will be midnight on the closing date stated above. if you need any assistance, please call kate pounds (recruitment team) on +44 (0) 23 8059 5456 or email email@example.com please quote reference 1297720af on all correspondence. the faculty of medicine holds an athena swan silver award demonstrating commitment to equal opportunities and gender balance in the workplace. the faculty recognises that applicants may seek flexible working patterns which will be considered as part of the recruitment process. for further information including key benefits designed to help maintain and support employees' well-being and work-life balance, please see our working with us website pages. email details to a friend
7 дней назад
theprincipalclinicaldatastandards specialistis responsiblefor the development, maintenance and implementation of industry (cdisc and regulatory) compliant clinical data standards, providing expert support tobusinessusers and teams on their usein line withthe clinical data standardsstrategy. they provideexpertsupport ensuringthe development, implementation and timely availability ofconsistent, high qualityclinical data standards deliverables supporting the acquisition and tabulation and/or analysis and reporting of clinical trial data across global libraries including; data collection tools in edc (crfs, edits checks, derivations, core configurations) anddata transfer specifications analysis data/tfl standards associated standard metadata, business rules and guidelines. major activities lead and contributetoclinical data standardsdefinition, development, validation and support within assigned standards discipline(domain)including the development and maintenance of associated metadata, documents, business rules andguidelines where applicable. page break define and deliver to robust, priority driven standards development plans for assigned area to ensure agreed deliverables are met and assigned resources are fully and effectively utilized. responsible for driving theefficient, high quality and timelyimplementation of new standardsand/orupdates to standardsfor: data acquisition and tabulation standards standards in clinical systems including edc, mdr and other global standards librariesincludingrobust testing and validation compliantdata models to supportthe use and transformation ofdata acquisition, tabulation and reviewstandards(including associated metadata). useadvanced database programming techniques tosupport the implementation of efficient data collection tools. processes, tools and guidelines relating to thesubmissionof standardizedacquisition/tabulation data supporting regulatory submission. or/and; analysis and reporting data standards compliantanalysisand reportingstandards(adam and tfl) useadvanced programming knowledge to support specification ofnew analysisandreporting tools (incl. standard macros) data models to support dataanalysis (adam) and reporting (tfl)standards(including associated metadata). processes, tools and guidelines relating to thesubmissionof standardized analysis data supporting regulatory submission. in collaboration with representatives across data operations disciplines and key stakeholder and partner functions within gdo and across global drug development,ensurethe accurate translation of scientific and analytical requirements into efficient, compliant standards. support and ensure the appropriate and efficientgovernanceand approval of global and project/study specific clinical data standardsliaisingwith governance boards as needed. contribute to the technical review and assessment of industry and regulatory standards and guidelines supporting regular gap/impact analysis and implementation of action plans where needed. communicate effectively with the partners and customers; establish and maintainstrongcollaborativerelationships withdata operations, biostatistics and clinical development groupssupporting the development and use of clinical data standards. lead and contribute to thedevelopment, maintenance andtraining of relevant clinical standardssystems and processes. act as an expertconsultantproviding clinical data standards input to all relevantareasincluding; electronic data capture/database programming, edit check programming, report programming, electronic data loads, ivr technology, electronic patient reported outcomes, metadata management and/or other clinical data management or analysis data and tfl-related systems. actassubject matter expert (sme) for assigned area providing support,consultationand training to end users and sme networks on implementation of standards and related tools ondevelopment programs. provide mentoring and technical guidance to clinical data standards associates. maintain up-to-date, expert knowledge of relevant technologies (edc, software languages, applications etc.), industry standards (e.g. cdisc, define.xml, ectd etc.) and regulatory guidelines. may represent novartis within industry wide associations and working groups; contributing to regulatory guidelines, industry practices and professional standards development organizations such as cdisc, cfast, phuse css, dia etc. as needed, act as a clinical standards representative supporting data standards governance, process improvement initiatives and/or other non-clinical projects. key performance indicators achieve overall goals as set each year by group head clinical standards. achieve high level of quality, timeliness and customer satisfaction onclinical data standards activities anddeliverables. achieve high levels ofeffective collaboration,customer satisfaction on support and training provided within discipline/area. achieveminimal number of post-production changes resulting fromclinical data standardsissues. no critical findings as result of routine audits or health authority inspections relating to activities/deliverables supported by the clinical standards group. impact on the organization: contribution to timely availability ofefficient, complaint and high quality clinical standards used across global drug development. contribution to external quality reputation of novartis (clinical sites and regulators). support/training for end usersonefficient implementation of reporting data standards. education(minimum/desirable): bs/ba/ms in computer science,management information systems,health sciences, statistics, or related field. languages: fluent english (oral and written). experience/professional requirement: at least 6 years industry experience in one of the following fields; edc development and implementation preferably using medidata-rave data managementclinical statistical programming using sas and cdisc data standards strong knowledge in one or more area of industry data standards and requirements including data acquisition, cdisc (cdash, sdtm, adam), reporting and analysis, regulatory data submission. experience in supporting development of clinical standards and associated guidelines. experttechnical skills relevant to; data acquisition and tabulation good knowledge of edc systems (preferably including medidata-rave) good knowledge in object oriented programming concepts knowledge of other programming languages such as visual basic, sql-pl/sql and c# or javapreferable data analysis and reporting goodknowledge of sas and other statisticalprogramming languages/software (e.g. r) good understanding ofstatistical programming/statistical concepts in clinical trials knowledge of other programming languages such as visual basic, sql-pl/sql, xml,pythonpreferable strongunderstanding and knowledge of regulatory requirements and industry standards relevant to data management and statistical programming (including gcp, ich) good project management and coordinationskills;strongproblem-solving, negotiation and conflict resolution skills. outstandinginterpersonal and written and oral communication skills, with the ability to effectively communicate cross-functionally. strongunderstanding of drug development, global clinical trial / project practices, procedures, methodologies. proven ability to provide and coordinate internal and external training(experience working in highly matrix teams and providing technical guidance). experience contributingtonon-clinical initiatives requiring clinical standards expertisepreferable. at iqvia, we believe in pushing the boundaries of human science and data science to make the biggest impact possible – to help our customers create a healthier world. the advanced analytics, technology solutions and contract research services we provide to the life sciences industry are made possible by our 67,000+ employees around the world who apply their insight, curiosity and intellectual courage every step of the way. learn more at jobs.iqvia.com.
University of Oxford
9 дней назад
based within the nuffield department of population health, the cancer epidemiology unit (ceu) seeks to provide large-scale reliable evidence on the relationships between common exposures and common conditions of public health importance such as prostate, breast, and colorectal cancers, cardiovascular disease and bone health. within the ceu, the key/travis group’s research is primarily based on large prospective epidemiological studies on hormones, nutritional, molecular and genetic markers in relation to prostate and breast cancer and other common non-communicable diseases. as a medical statistician you will work as part of this research team and in close collaboration with epidemiologists designing and implementing appropriate methods for the analysis of data arising from research projects on risk factors for common non-communicable diseases, in particular cancer. your responsibilities will include planning and implementing statistical analysis/programming on data from studies in the cancer epidemiology unit (including cohort studies, case-control studies, individual participant meta-analyses and mendelian randomization analyses), database management and the preparation of datasets for analyses. you will also prepare tables and figures, reports summarizing datasets and results, contribute to reports and articles for publication in peer-reviewed journals, and prepare other data and analysis-related documents as required. to be considered, you will hold a bachelor’s degree in mathematics, statistics or other relevant subject and a postgraduate degree in a statistics-related subject or epidemiology, or have equivalent experience. you will also have a demonstrated understanding and experience of a range of statistical concepts and techniques (e.g. linear, logistic and cox regression models), programming skills in a statistical language, such as stata, r/s-plus or sas, and good organizational, time management and communication skills, with an ability to work to tight deadlines calmly and efficiently. informal enquiries should be addressed to associate professor ruth travis (firstname.lastname@example.org). the position is full time (part time considered) and fixed term for 2 years. the closing date for applications is noon on 13th november 2020.